SR-121463A CAS; 185913-79-5

详细信息

价格:6600元/公斤含量:99% 包装:25公斤

CAS;185913-79-5

分子式：C17H22ClNO3

分子量：323.8228

The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives

3-(methoxymethoxy)pentane-1,5-diol (II), which is treated with Ts-OH and TEA in

THF to yield the disulfonate (III). The condensation of (III) with 5-

ethoxyindolin-2-one (IV) by means of tBu-OK in THF affords the spiro compound

(V), which is deprotected with HCl in methanol to afford the spiranic alcohol

(VI). The oxidation of (VI) with pyridinium chlorochromate (PCC) over Al2O3

provides the spiranic cyclohexanone (VII), which is treated with 2-chloroethanol

(VIII) and Ms-OH in toluene to give the ketal (IX). The reaction of (IX) with

zinc borohydride and trimethylsilyl chloride in ethyl ether/dichloromethane

yields the 2-chloroethoxy derivative (X), which is condensed with 4-(N-tert-

butylcarbamoyl)-2-methoxybenzenesulfonyl chloride (XI) by means of tBu-OK in THF

to afford the adduct (XII). Finally, the target compound is obtained by

condensation of (XII) with morpholine (XIII) by means of NaI in DMF, followed by

treatment with fumaric acid.

尼朦尔可素包装:50克/瓶价格:1300元/瓶红色粉末

还阳碱 CAS号：171596-29-5 8600元/公斤

金阳碱 CAS号：54060-92-3 18850-57-5 4600元/公斤

新阳碱 36-12-87 4600元/公斤

虾青素 CAS号：472-61-7 8600元/公斤

CAS号：1445583-51-6

MAB-CHMINAC 1454266-19-3

5FADB 1715016-75-3

FUB-AMB 1715016-76-4

CAS号：70434-92-3 CP 47,497 CAS号：952016-47-6 8492312-32-2

CAS号：84485-00-7 1216544-25-0 125494-59-9 CAS：16359-54-9 CAS：18305-29-8

原料与成品三包服务: CAS:90717-16-1;299-42-3;6740-85-81867-66-9;51062-14-7;

CAS:2114-00-3;2011-67-8;5650-44-2;103-79-7 CAS:4468-48-8;103-79-7;51-57-0;6740-

88-1;936-59-4;60124-79-0;125-79-1 CAS:76-99-3;118-92-3;2538-50-3;340-56-7;82-58-

6;51753-57-2;58-08-2

+Q:17OO;2782;O6